Understanding the Difference Between Respiratory Reflux and GERD: Beyond Heartburn
At-A-Glance
- Respiratory reflux (previously called LPR) primarily affects the throat, sinuses, airways, voice swallowing, postnasal drip, and breathing, and it often occurs at night during sleep, with no heartburn, day or night.
- GERD primarily affects the esophagus, and its hallmark symptom is heartburn.
- If you think you may have respiratory reflux, the doctor you should see is an otolaryngologist (ENT); gastroenterologists know virtually nothing about respiratory reflux.
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Respiratory reflux and Gastroesophageal Reflux Disease (GERD) are distinct conditions that are often confused. While both involve acid reflux, their symptoms, affected areas, and treatments differ significantly. This comprehensive guide explains the key differences between these conditions.
Key Differences at a Glance
Respiratory Reflux (LPR):
Primarily affects breathing and throat
Usually no heartburn symptoms
Often occurs silently during sleep
Normal esophagus in 83% of cases
Poor response to standard GERD treatments, including PPIs
Symptoms include hoarseness, chronic cough, and breathing difficulties
GERD:
Primarily affects the esophagus
Characterized by heartburn and indigestion symptoms
Symptoms are typically noticeable
Esophageal involvement
Usually responds to conventional acid-suppressing treatments
Historical Context and Evolution
The term “gastroesophageal reflux disease” (GERD) emerged in the 1970s when gastroenterologists focused primarily on esophageal symptoms. However, in 1987, I introduced the term “Laryngopharyngeal Reflux” (LPR) to describe a distinct pattern of reflux affecting the throat and airways. By 2017, I felt that we needed a more comprehensive term, respiratory reflux, to better encompass the condition’s full scope.
Current Healthcare Challenges
Medical Training Gap:
Most airway specialists (pulmonologists, otolaryngologists, allergists) lack training in respiratory reflux. Primary care physicians often aren’t equipped to diagnose or treat respiratory reflux. And gastroenterologists focus almost exclusively on heartburn and GERD.
Diagnostic Differences:
Only about 15% of patients show overlap with GERD and respiratory reflux. Traditional gastroenterology GERD tests cannot diagnose respiratory reflux. Different diagnostic approaches and technology are needed for each condition.
Treatment Implications
GERD Patients Typically Benefit From:
Standard acid-suppressing medications
Gastrointestinal-focused treatments
Care from gastroenterologists
Respiratory Reflux Patients Often Require:
Different treatment approaches focusing on diet and lifestyle
Specialized care beyond traditional GERD protocols
Potentially multi-disciplinary (primary care and otolaryngology) management
Call for Healthcare Policy Changes
The Medical Community Needs to Recognize:
(1) Respiratory reflux is distinct from GERD.
(2) The current healthcare structure may not adequately address respiratory reflux.
(3) Medical education should include specific training for respiratory reflux.
(4) Insurance and Medicare policies should reflect the distinctions between respiratory reflux and GERD.
(5) Specifically, Medicare should increase reimbursement for TNE (transnasal esophagoscopy) to make it competitive with sedated endoscopies by gastroenterologists. There should be no facility fees because TNE should be an office-based procedure and the procedure of choice for esophageal screening.
Conclusion
Understanding the difference between respiratory reflux and GERD is crucial for proper diagnosis and treatment. While GERD primarily causes heartburn and digestive symptoms, respiratory reflux affects the airways and throat, often without traditional reflux symptoms. At this time, most patients with acid reflux have respiratory reflux, not GERD. Healthcare policies and medical training need to evolve to better address these respiratory reflux.
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